Therapeutic use of Fisetin and Fisetin Loaded on Mesoporous Carbon Nanoparticle (MCN) in Thioglycollate-induced Peritonitis
نویسندگان
چکیده
منابع مشابه
Prophylactic Use of Fisetin in Thioglycollate-Induced Peritonitis in Mice
Infectious or non-infectious peritonitis leads to systemic inflammation due to violation of the peritoneum which is often fatal. Fisetin, a flavonol compound, exhibits a broad spectrum of biological activities including anti-oxidant, anti-inflammatory, anti-cancer and neuro-protective effects. It was used in a murine model of thioglycollate (TG)induced aseptic peritonitis to investigate its ant...
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Objective(s): Bacterial cellulose (BC) has applications in medical science, it is easily synthesized, economic and purer compared to plant cellulose. The present study aimed to evaluate BC, a biocompatible natural polymer, as a scaffold for the bone marrow mesenchymal stem cells (BMSCs) loaded with fisetin, a phytoestrogen.Materials and Methods: BC hydrogel scaffold was prepared from Gluconacet...
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Increasing evidence suggests that inflammatory processes in the central nervous system that are mediated by microglial activation play a key role in neurodegeneration. Fisetin, a plant flavonol commonly found in fruits and vegetables, is frequently added to nutritional supplements due to its antioxidant properties. In the present study, treatment with fisetin inhibited microglial cell migration...
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BACKGROUND The anti-tumor activities of Natural compounds and their derivatives are of great interest to pharmaceutical industries. Fisetin is one of prospective natural compounds in this regard but unfortunately with poor hydrophilicity. METHODS The effects of unmodified and modified fisetin in cultured ovarian cancer cells were compared by transmission electronmicroscopy to determine apopto...
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Diabetes is characterized by a proinflammatory state, and several inflammatory processes have been associated with both type 1 and type 2 diabetes and the resulting complications. High glucose levels induce the release of proinflammatory cytokines. Fisetin, a flavonoid dietary ingredient found in the smoke tree (Cotinus coggygria), and is also widely distributed in fruits and vegetables. Fiseti...
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ژورنال
عنوان ژورنال: Journal of Nanomedicine & Nanotechnology
سال: 2015
ISSN: 2157-7439
DOI: 10.4172/2157-7439.1000332